D81Combined immunodeficiencies
Code usage status
Primary diagnosis
Select a more specific code
Apply only when it matches the confirmed diagnosis and the documented clinical record.
Specificity
Do not use D81 directly
Use the most specific code supported by the record.
- Chapter III
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Group D80-D89
- Certain disorders involving the immune mechanism
- Official Vietnamese name
- Suy giảm miễn dịch kết hợp
- Additional WHO coding guidance
- Excl.: autosomal recessive agammaglobulinaemia (Swiss type) (D80.0)
Related D81 codes
D81.0
Primary diagnosis candidate
Severe combined immunodeficiency [SCID] with reticular dysgenesis
D81.1
Primary diagnosis candidate
Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
D81.2
Primary diagnosis candidate
Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
D81.3
Primary diagnosis candidate
Adenosine deaminase [ADA] deficiency
D81.4
Primary diagnosis candidate
Nezelof syndrome
D81.5
Primary diagnosis candidate
Purine nucleoside phosphorylase [PNP] deficiency
D81.6
Primary diagnosis candidate
Major histocompatibility complex class I deficiency
D81.7
Primary diagnosis candidate
Major histocompatibility complex class II deficiency
D81.8
Primary diagnosis candidate
Other combined immunodeficiencies
D81.9
Primary diagnosis candidate
Combined immunodeficiency, unspecified
Clinical record checklist
View coding guide →- Confirm that the code matches the final documented diagnosis.
- Use one primary-diagnosis code and record only relevant additional conditions.
- Review Ministry indicators, inclusions, exclusions and notes.
- Do not infer a diagnosis beyond the clinical record.
2026 regulatory basis
Indicators are taken from columns 24–29 of the classification accompanying Circular 06/2026/TT-BYT, cross-referenced with Decision 1849/QĐ-BYT and Official Dispatch 4059/BYT-BH.
